Decoction of ewe eje or its leaf extract can lower serum cholesterol and get rid of bad cholesterol (LDL). Make sure to follow the package instructions carefully. The present study investigated the antioxidant and in vitro antidiabetic capacities of Justicia carnea aqueous leaf extract (JCAE) using -amylase inhibition model. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. When it comes to fertilizing, an NPK balance of 5-10-5 will work well, encouraging blooming and strong growth. Mr. K.O. This is why you should avoid potting them if you live in colder areas. Olaniyan JM, Hadiza LM, Hussaini AM, Musa BB, Abubakar SA. Authors KOK and ESA performed the statistical analysis and managed the analyses of study. Justicia carnea (belonging to Acanthaceae family) is a flowering plant consisting ~600 species that are widely distributed in the tropics and subtropics [7]. After 72h of soaking, the wine (dark purplish red) colored filtrate was filtered using a double cheese cloth, concentrated under reduced pressure using rotary evaporator and subsequently water bath at 40C to obtain a slurry (dark purple) extract termed Justicia carnea ethanol extract (JCEE). Google Scholar. Becoming a contributing member of Gardenia is easy and can be done in just a few minutes. 9 health benefits of justicia carnea - Herbconer Hepatoprotective Effect of Methanol Extract of Justicia carnea Leaves Results obtained from the acute oral toxicity study revealed tolerance of experimental rat to acute administration of J. carnea ethanol extracts since no mortality and signs of toxicity were observed after 24h (Table1). Phytochemical screening and Gas Chromatography-Mass Spectrometry (GC-MS) analysis indicated presence of . Ogwu obara can act as a blood tonic for women during menstruation. Studies on The Phytochemical and Nutritional Composition of Aqueous California Privacy Statement, Excitedly, scientific studies have supported the traditional claims. 4. Materials and Methods Plant material Justicia carnea leaves used in this study were collected from Ozalla Isuofia in Anambra State and identified by Mr. Ozioko Assessment of Aloe vera (L) genotoxic potential on Escherichia coli and plasmid DNA. Extinction coefficient () of MDA TBA complex=1.56105M1cm1. The absorbance was read at 412nm against the reagent blank. The leaves of Justicia carnea contains powerful antioxidant activities and phytochemical components that help reduce oxidative stress, and reduce the risk of development of cancer. Google Scholar. Lorke D. A new approach to practical acute toxicity testing. Oral acute toxicity study on J. carnea ethanol extract (JCEE) was carried out according to Lorke [15] method using the total of twelve (12) albino rats in two phases. When properly boiled in water, the aqueous leaf extract turns red, and when mixed with milk turns pink. There are several claims that justicia carnea can prevent epilepsy and convulsion among children. While every effort has been made to describe these plants accurately, please keep in mind that height, bloom time, and color may differ in various climates. The spectacular rosy plumes of the flamingo-colored flower are distinctive and attract hummingbirds to pollinator gardens. Evid Based Complement Alternat Med. Another strong benefits of justicia carnea leaves is in lipid profile. J. Appl. In the kidney, SOD and MDA level were indistinguishable compared to the control except SOD level in rats that received 800mg/kg JCEE that reduced significantly (p<0.05). However, serious caution of the dose should be taken into consideration when extrapolating this result for human consumption. Turn off the heat and then soak the leaves into the pot. The findings show that ethanol extracts of Costus afer and Justicia carnea could operate as main antioxidants and free radical scavengers. So lets go through this together. Sci. PDF Evaluation of Anti-inflammatory and Analgesic Properties of Justicia They look terrific in properly shaded outside areas such as porches, patios, driveways, and entryways. Ewe eje or Ewe ajeri is known by the Igbo tribe as Ogwu obara. what are the pros and cons of testosterone replacement therapy? 3 . Biomed Res. Macrocytic and hypochromic anemia usually results due to increased mean corpuscular volume (MCV) and decrease in mean corpuscular hemoglobin concentration [30]. Vitamin C and E are antioxidants. [4].Inflammationinjuries, in an attempt to heal is presented by five cardinal signs of heat (calor), redness (rubor), swelling (tumor), pain (dolor) and loss of function5.Studieshave demonstrated inflammation as being caused by View abstract. Justicia carnea is amedicinal plant used widely in Nigeria which is reported to have diverse functions, including blood-boosting potential. The plant is transplanted in the spring. International Journal of Biochemistry Research & Review. The resultant liquid would turn crimson red. This special leaf can be found around us- in our neighborhood. Gas chromatography/mass spectrometry of simple coumarins, 3-phenylpropionic acids and their hydroxy and methoxy derivatives. Phytochemical profile, antioxidant, -amylase inhibition, binding Buege JA, Aust SD. Paradoxically, oxidation of GSH has been reported to occur when GSH interact with metal ions thereby generating superoxide anions from the transfer of electrons from the metal ions to molecular oxygen [32]. The higher LD50 (>5000mg/kg body weight) of J. carnea leaf ethanol extract suggested that the ethanol extract is experimentally safe and not toxic. Generally disease free. Duan WL, Liang XM. Extraction was carried out by maceration (72h) following the method of Onoagbe et al., [13]. This plant is somewhat drought-tolerant once established but looks best with regular watering during periods of extended dry weather. It is also known as Jacobinia carnea, and is a part of the Acanthaceae family along with the Aphelandra squarrosa (Zebra plant) and Crossandra. Anthonia OC, Ikechukwu UR, Uzoma NO, Sunday ELU. The LD50 of extract was greater than 5000mg/kg body weight. Previously, J. carnea leaf has been reported to contain high quantity of phytochemical constituents (such as saponins, alkaloids and terpenoids), vitamins (A, C and E) and minerals [9, 10]. These antibodies help prevent infections and fight off diseases. Justicia Carnea; Blood-Boosting Green Plant That Turns Hot Water Red! 1978;90:819. Treatments of all experimental animals were performed following Principle of Laboratory Animal Care manual guidebook of National Institute of Health as approved by the Research Ethics Committee of Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State. 50mg/kg-1200mg/kg treatment relative to control treatment showed varied degree of renal injury that is dose dependent. The spread is equally glorious and can take up 12 15 inches of space. J Nat Prod 1988;51(4):804-805. Adetuyi is a Professor of Biochemistry in the Department of Chemical Sciences, Faculty of Sciences, Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State, Nigeria. The absorbance of the supernatant was measured against reagent blank at 532nm. Article Anti-depressant-like effect of kaempferitrin isolated from Justicia spicigera Schltdl (Acanthaceae) in two behavior models in mice: evidence for the involvement of the serotonergic system. Hence, Justicia carnea can be used to strengthen the immune system. 3. CAS The resultant liquid after boiling is usually crimson red. 2008;108(9):14807. 2018;2018:5762368. J Nat Prod 1988;51(3):599-600. No observable focal sclerosis of renal glomeruli, capsular spaces around the glomerulus appears normal with distinct layering of renal microcellular structures. The liver and kidneys excised from all the experimental rats were fixed in a labeled sample bottles containing 10% formalin and processed for histological examination. CAS Afr J Tradit Complement Altern Med. The unique flower clusters and bright coloring has made it a popular choice among landscape artists and amateur gardeners as well. They also maintain our skin tone and texture, and help in reproductive functions. Sinha AK. Ren Fail. Note: A=change in absorbance, TV=total volume, SV=sample volume, TP=total protein, =molar extinction =1.34104M1 cm1. https://doi.org/10.4314/njps.v19i1.32627. However, coadministration of both extracts exerts a synergistic effecton the . Create a beautiful garden with this colorful and Use our interactive toolsto design your dream garden. Ewe eje can also be used to manage abnormalities associated with anaemia and for the treatment and management of diabetics. Side Effects, Uses and Health benefits of Ewe eje (Justicia carnea leaf), The exact topic of this article first appeared on www.nimedhealth.com.ng. Clinical Guide to Laboratory tests. Chariandy, C. M., Seaforth, C. E., Phelps, R. H., Pollard, G. V., and Khambay, B. P. Screening of medicinal plants from Trinidad and Tobago for antimicrobial and insecticidal properties. This later condition is termed insulin resistance. Rats were routinely observed for signs of toxicity. Estimation of total, protein-bound, and non-protein sulfhydryl groups in tissues with Ellmans reagent. Summer temperatures above 77 degrees Fahrenheit (25 C) are perfect. Justicia Carnea Care: How To Grow Brazilian-Plume Onoagbe IO, Attah V, Luther MM, Esekheigbe A. Hypoglycemic and anti-diabetic effects of Morinda lucida and Tetracera alnifora in normal and streptozotocin-induced diabetic rats. Haematological and biochemical studies on Justicia carnea leave extract in phenylhydrazine induced-anemia in albino rats. Methods. long (20 cm), densely packed with pink to crimson tubular flowers. Justicia carnea is a popular ornamental plant, which possesses powerful medicinal values. Caterpillars may be an occasional problem, chewing down on some of the foliage. Brazilian-plumeflowers are best propagated from softwood cuttings. National Research Council. Stover PJ, Caudill MA. However, watch out for nematodes and spider mites. PDF Haematological and Biochemical Studies on Justicia Carnea Leaves Anal Biochem. Braz. It has been reported previously that under certain conditions, dietary antioxidants such as ascorbic acid, tocopherol and carotenoids could act, occasionally, as pro-oxidants to initiate slight degree of oxidative stress microenvironment. Saunders; 1995. p. 26873. There are several scientific studies which show that the methanolic leaf extract of Justicia carnea protects the liver from toxic effect of carbon tetrachloride harmful effect on the live integrity and functions. Cookies policy. Liver superoxide dismutase (SOD) activity was significantly (p<0.05) increased at 1200mg/kg while other tested doses caused no detrimental effect on glutathione, catalase, SOD and malondialdehyde level in liver and kidney. https://doi.org/10.3390/molecules191221442. Justicia carnea is a medicinal plant that is used conventionally as blood tonic from time immemorial in Nigeria. Inhibitory Potential and Antidiabetic Activity of Leaf Extracts of Justicia carnea. This encourages better flowering and bushier and denser new growth. Prevent this by spraying the leaves with water. The liver and kidneys were excised and rinsed immediately in a normal saline (0.9% Nacl) to remove blood stain, dried between layers of Whatman filter paper, weighed and homogenized to obtain the supernatant for biochemical analysis. Colorimetric assay of catalase. In traditional medicine, justicia carnea is used in treating hepatitis. hindawi publishing corporation evidence-based complementary and alternative medicine. Cut back after flowering to 2-3 nodes from the ground to keep the plant bushy and promote new blooms. The animals were allowed free access to rat chow and water ad libitum. Pot the specimen and bring it indoors to add a bright touch of color to your interiors. Why urban citizens in developing countries use traditional medicines: the case of suriname. Decreased white blood cell count was obtained in this report, the level of lymphocyte and granulocyte was not altered by the extract while MID sized cell was significantly elevated at 500 and 800mg/kg dose. Molecules (Basel, Switzerland), 19(12), 2144221461. Part shade is the ideal growing condition for Brazilian plumes. Some people would rather chew the leaves, while others add to meals or brew into a tea (in combination with other plants). Too much fertilizer is damaging for your plant. These compounds beyond boosting your blood concentration, thereby enhancing the transport of nutrients to various parts of the body, also boost your immune system against several infectious diseases. 16. Justicia carnea (ewe eje) is used by pregnant women to boost the production of red blood cells and cure anemia in pregnancy. The findings back up local assertions that they can be. The weight of liver and kidney of rats were measured immediately after excising the organs and is presented in Table2. In subacute study, rats were randomized into six groups of five rats per group: Group 1 (control) received distilled water, group 2, 3, 4, 5, 6 received 50, 100, 500, 800 and 1200mg/kg body weight of J. carnea ethanol extract once daily using oral gavage.

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